What are the ovulation pills? Types of ovulation pills

What are the ovulation drugs? Many infertile families succeeded in getting pregnant by taking ovulation drugs. Today, I will give you a detailed introduction to the types of ovulation-promoting drugs. Different ovulation drugs are suitable for different symptoms. Families preparing for pregnancy need to follow the doctor's guidance to choose.

Types of ovulation pills

(1) Clomiphene: The drug of choice for inducing ovulation, used for various types of anovulation other than hyperprolactinemic infertility.

(2) Human gonadotropin (HMG): It can be used for infertile patients who do not respond well to clomiphene. The intra-individual and inter-individual variability of this drug is large, and B-ultrasound monitoring is required to understand the development of follicles and prevent the occurrence of ovarian hyperstimulation syndrome.

(3) Human Chorionic Gonadotropin (HCG): It has LH-like effects and is often used in combination with the above-mentioned ovulation-inducing drugs to promote the final maturation of follicles and ovulation.

(4) Progynova: Symptoms of menopause after menopause, or symptoms of estrogen deficiency after oophorectomy and radioactive castration for non-cancerous diseases, such as hot flashes, paroxysmal sweating, sleep disorders, depression, irritability, headaches, and dizziness

(5) Gonadotropin-releasing hormone (GnRH): Applicable to hypothalamic anovulation. It needs to simulate the natural release of GnRH in the body and is administered by intravenous pulse injection. It is expensive and inconvenient, so it is rarely used.

What are the ovulation-stimulating drugs?

Clomiphene: Starting from the 5th day of menstruation, take clomiphene 50-150 mg/day orally for 5 consecutive days. Ovulation may occur 5-11 days after stopping the drug. If the estrogen level is low, you can first use a small dose of estrogen, diethylstilbestrol 0.125-0.25 mg/day, for 20 consecutive days, and apply it for 1-3 cycles to increase the sensitivity of the hypothalamus-pituitary-ovarian system, and then use clomiphene to promote ovulation, which can improve the efficacy. If the cervical mucus is small and viscous, after taking clomiphene, add diethylstilbestrol 0.125-0.25 mg/day for 7 consecutive days.

Artificial cycle of estrogen and progesterone: For those with general menstrual disorders but with a certain level of estrogen, estrogen and progesterone can be used sequentially for artificial cycle treatment for 3 months. Ovulation may occur after stopping the medication.

Human chorionic gonadotropin (HCG): HCG has the effect of luteinizing hormone and can induce ovulation when administered when the follicles are nearly mature.

Luteinizing hormone-releasing hormone (LH-RH): Suitable for anovulators with hypothalamic insufficiency. Use micro-pump pulse intravenous injection, pulse interval 90-120 minutes, small dose 1-5μg/pulse, large dose 10-20μg/pulse, medication for 17-20 days, or from the 5th day of the menstrual cycle, daily intramuscular injection of 50μg, for 7-10 consecutive days.

Bromocriptine: Suitable for patients with anovulation and hyperprolactinemia.

Who needs to take ovulation pills?

For women who can get pregnant normally, taking ovulation-stimulating drugs is actually unnecessary and dangerous. As a clinical drug, ovulation-stimulating drugs were originally used to treat infertility and are mainly suitable for the following situations:

1. Hypothalamic disorders: There are functional and organic types. The former include idiopathic diencephalic amenorrhea, functional hyperprolactinemia, psychogenic amenorrhea, and anorexia nervosa; the latter include diencephalic tumors, post-head trauma, and post-encephalitis.

2. Pituitary dysfunction: pituitary adenoma, tuberculosis or syphilitic granuloma, Sheehan syndrome.

3. Ovarian dysfunction: including primary ovarian amenorrhea and secondary amenorrhea. The former includes Turner syndrome, etc. The latter includes organic ovarian damage, premature ovarian failure, etc., such as ovarian function damage caused by tumors, inflammation, etc.