What medicine can reduce neonatal jaundice? What medicine is effective for neonatal jaundice?

The baby was born not long ago, and he has developed jaundice in the past few days. His parents are very worried. So what medicine can reduce the jaundice of the newborn? What medicine is effective for newborn jaundice?

What medicine should I take for neonatal jaundice?

Western medicine

1. Glucose and alkaline solutions: Glucose can provide heat to children, nourish important organs such as the heart, liver, and brain, and reduce metabolic acidosis. When acidosis occurs, the blood-brain barrier opens, which increases the amount of bilirubin entering the brain tissue. Alkaline solutions should be transfused in time to correct acidosis and prevent bilirubin encephalopathy.

2. Plasma or albumin: Providing albumin linked to bilirubin can reduce free unconjugated bilirubin and prevent bilirubin encephalopathy. Plasma 25ml/time intravenous injection or albumin 1g/kg plus 25% glucose 10-20ml intravenous drip, 1-2 times a day.

3. Enzyme inducers: can induce the activity of glucuronyl transferase in the smooth endoplasmic reticulum of hepatocytes and reduce serum unconjugated bilirubin. Phenobarbital can also increase Y protein and promote the uptake of bilirubin by hepatocytes. Phenobarbital 5-8 mg/kg per day, nikethamide 100 mg/kg per day, both taken orally 3 times. Because it takes 2-3 days for the drug to show efficacy, it is necessary to take the drug as soon as possible. The two drugs can be used together to improve the efficacy.

4. Adrenal cortical hormone: It can prevent antigen-antibody reaction and reduce hemolysis; it can also promote the binding ability of hepatocyte glucuronyl transferase to bilirubin. Prednisone 1-2 mg/kg per day, divided into three times orally, or hydrocortisone 6-8 mg/kg per day or dexamethasone 1-2 mg per day plus 10% glucose 100-150 ml intravenous drip.

traditional Chinese medicine

Traditional Chinese medicine can reduce jaundice, and in vitro tests have shown the effect of suppressing immune response. Commonly used prescriptions include:

1. Sanhuang Decoction: 4.5g of Scutellaria baicalensis, 1.5g of Coptis chinensis, and 3g of processed Rhubarb.

2. Yinchenhao Decoction: Yinchen 1.5g, Gardenia 9g, processed rhubarb 3g, and licorice 1.5g.

3. Xiaohuang Lidan Granules, Artemisia capillaris 9g, Gardenia 3g, Rhubarb 3g, Imperatae rhizome 10g, Centella asiatica 6g, Poria 6g.

You can choose any one of the above three prescriptions, take one dose daily, divided into several doses before breastfeeding.

What should you pay attention to when you have jaundice?

1. Pay attention to the degree of jaundice: If the skin below or on the abdomen turns yellow, or the skin turns yellow very quickly (such as when the yellowing quickly spreads from the face to the chest and abdomen), you need to seek medical attention. In addition, if jaundice occurs within 24 hours of birth, or if a full-term baby has jaundice for more than 1 to 2 weeks, or a premature baby has jaundice for more than 2 to 3 weeks, it is also a manifestation of pathological jaundice, and it is best to seek medical attention.

2. Pay attention to the possible symptoms of pathological jaundice: including vomiting, pale skin, decreased vitality, loss of appetite, abdominal distension, diarrhea, fever, dark tea-colored urine, white stool color (Note 2), etc. If any of the above conditions occur, seek medical attention immediately.

3. Pay attention to certain factors that aggravate jaundice: such as premature birth, hypoxia during delivery, family history of hemolytic diseases (such as favism), and possible infections in the baby before or after birth (such as fever and infection in the mother before delivery, early rupture of membranes). These are also matters that need attention, and inform the doctor of this medical history when sending the baby to the hospital.

(Note 2) If the stool becomes grayish white or the urine becomes dark brown, it may be a congenital biliary disease, which can be serious enough to require a liver transplant or even be life-threatening, so you need to pay more attention.

Baby jaundice care

1. Let the baby's meconium be discharged as soon as possible: In the early stage, we should feed the newborn as soon as possible to discharge the meconium as soon as possible, because the meconium contains a lot of bilirubin. If the meconium is not discharged cleanly, the bilirubin will be reabsorbed into the blood through the special enterohepatic circulation of the newborn, causing jaundice to increase. How to see if the meconium is discharged cleanly? The main thing is to see if the meconium changes from black to yellow, which means it is discharged cleanly.

2. Give the newborn baby enough water: The way to judge whether the newborn baby has enough fluid intake is to look at the newborn baby's urine. Generally, a normal newborn baby urinates 6-8 times a day. If the frequency is less than that, it is possible that his fluid intake is not enough. Too little urine is not conducive to the excretion of bilirubin. We should ensure the newborn baby's fluid intake. Generally, the meconium of the newborn baby should be excreted in 2-3 days, which can reduce the degree of jaundice.

3. Pay attention to observe: the systemic symptoms of infants with fetal jaundice, such as mental depression, drowsiness, difficulty in sucking, restlessness, staring, limb rigidity or convulsions, so as to detect and treat seriously ill infants early. Closely observe the heart rate, heart sounds, degree of anemia and changes in liver size to prevent and treat heart failure at an early stage.

4. Pay attention to cleanliness: Keep the baby's skin, umbilicus and buttocks clean to prevent damage and infection. When blood transfusion therapy is required, the air in the ward should be disinfected in time, blood and various medicines and items should be prepared, and the operating procedures should be strictly followed.